Some notable general health organisations recommend against annual examinations, and propose a frequency adapted to age and previous examination results (risk factors).<>]<>]<>] The spemedecinet American Cancer Society recommends a cancer-related health check-up annually in men and women older than 40, and every three years for those older than 20.<>]
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With the clues obtained during the history and physical examination the healthcare provider can now formulate a differential diagnosis, a list of potential causes of the symptoms. Specific diagnostic tests (or occasionally empirical therapy) generally confirm the cause, or shed light on other, previously overlooked, causes.